@article {7364,
	title = {The distribution of an avt v1a receptor in the brain of a sex changing fish, epinephelus adscensionis},
	journal = {Journal of Chemical Neuroanatomy},
	volume = {42},
	number = {1},
	year = {2011},
	month = {2011///},
	pages = {72 - 88},
	abstract = {The present study describes the distribution of an arginine vasotocin (AVT) V1a receptor (AVTr) throughout the brain of a sex-changing grouper, rock hind Epinephelus adscensionis. The objectives of this study were to describe the AVTr distribution in the brain of rock hind for potential linkages of the AVT hormone system with sex-specific behaviors observed in this species and to examine sex-specific differences that might exist. An antibody was designed for rock hind AVTr against the deduced amino acid sequence for the third intracellular loop. Protein expression, identified with immunohistochemistry showed high concordance with mRNA expression, identified with in situ hybridization. AVTr protein and mRNA expression was widely distributed throughout the brain, indicating that AVT may act as a neuromodulator via this V1a receptor subtype. AVTr protein and mRNA were present in regions associated with behavior, reproduction and spatial learning, as well as sensory functions such as vision, olfaction and lateral line sensory processing. We observed high AVTr expression in granular cell formations in the internal cellular layer of olfactory bulbs, torus longitudinalis, granular layer of the corpus cerebellum, valvula of the cerebellum, nuclei of the lateral and posterior recesses, and granular eminence. High protein and mRNA expression was also observed in the preoptic area, anterior hypothalamus, and habenular nucleus. No obvious sex differences were noted in any region of the rock hind brain. ?? 2011 Elsevier B.V.},
	keywords = {Hermaphroditism, Immunohistochemistry, In Situ Hybridization, Rock hind, Social Behavior, Vasotocin receptor},
	isbn = {1873-6300 (Electronic) 0891-0618 (Linking)},
	author = {Kline, Richard J. and O{\textquoteright}Connell, Lauren A. and Hofmann, Hans A. and Holt, G. Joan and Khan, Izhar A.}
}
